Dr. Aditya K Sharma is presently serving as an Assistant Professor in the School of Biological and Biomedical Sciences at Galgotias University, a position he joined in July 2024. He is a self-driven scientist with comprehensive accomplishments in teaching and research. He is an innovative thinker with strong molecular biology, biochemistry, cell biology and machine learning acumen. He has 8+ years of experience in academic research with specialization in infectious biology, molecular biology, oncology and machine learning.

Research Area of Dr. Sharma focused on how bacteria abrogates host innate immune responses for its survival. Also, decipher how signalling mechanism differentially regulates the autophagy and inflammasome activation in macrophage and hepatocytes with bacterial infection including Ehrlichia and Mycobacterium infection.

Qualification

• Ph.D, Institute of Genomics & Integrative Biology, Delhi, India
• M.Sc. Biotechnology, Jamia Millia Islamia, Delhi, India.
• B.Sc. Biomedical Science, University of Delhi, Delhi, India.

Awards and Achievements

Academic:

• Reviewed research articles for prestigious journals.
• Served as a topic editor for reputed journals.
• Served as an executive board member of UIC PDA committee (2022).
• Received UIC postdoctoral and UIC travel award in 2022.
• Served as a Judge at ABRCMS E-Poster Spring Symposium, which is organized by the American Society for Microbiology (2022, 2023)
• Served as a Judge at 2022 GEMS Research Symposium at the University of Illinois, Chicago.
• CSIR - India Ph.D program research fellowship to pursue Ph.D program in India.

Area of Interest

microbiology; computational biology; bacterial drug resistance; cancer biology; machine learning.

Research Publications

Dr. Sharma has 14 research publications in International Journals, and 2 book chapters. Out of 14 research paper, Dr. Sharma has 5 first author and 3 corresponding papers*.

Research Publications

1. Kyle R Bohnert, Praneeth Goli, Anirban Roy, Aditya Kumar Sharma, Guangyan Xiong, Yann S Gallot, and Ashok Kumar. (2019). The Toll-Like Receptor/MyD88/XBP1 Signaling Axis Mediates Skeletal Muscle Wasting during Cancer Cachexia, Mol Cell Biol, 39. doi: 10.1007/s42690-023-01035-1
2. Neha Dubey, Mehak Zahoor Khan, Suresh Kumar, Aditya Kumar Sharma, Lahari Das, Asani Bhaduri, Yogendra Singh, and Vinay Kumar Nandicoori. 2021. 'Mycobacterium tuberculosis peptidyl prolyl isomerase a interacts with host integrin receptor to exacerbate disease progression', The Journal of Infectious Diseases, 224: 1383-93.
3. Neha Dubey, Raja Singh, Aditya Kumar Sharma, Sharmila Basu-Modak, and Yogendra Singh. 2015. 'The Survivors of the Extreme: Bacterial Biofilms', Microbial Factories: Biodiversity, Biopolymers, Bioactive Molecules: Volume 2: 161-82.
4. Nahed Ismail, Aditya Kumar Sharma, Lynn Soong, and David H Walker. 2022. 'Review: Protective Immunity and Immunopathology of Ehrlichiosis', Zoonoses (Burlingt), 2.
5. Anirban Roy, Aditya Kumar Sharma, Kushal Nellore, Vihang A Narkar, and Ashok Kumar. 2020. 'TAK1 preserves skeletal muscle mass and mitochondrial function through redox homeostasis', FASEB BioAdvances, 2: 538.
6. Aditya Kumar Sharma, Neha Dhasmana, Neha Dubey, Nishant Kumar, Aakriti Gangwal, Meetu Gupta, and Yogendra Singh. 2017. 'Bacterial Virulence Factors: Secreted for Survival', Indian J Microbiol, 57: 1-10.
7. Aditya Kumar Sharma, Abdeljabar El Andaloussi, and Nahed Ismail. 2023. 'Evasion of host antioxidative response via disruption of NRF2 signaling in fatal Ehrlichia-induced liver injury', PLoS Pathog, 19: e1011791.
8. Aditya Kumar Sharma, and Nahed Ismail. 2023a. 'Role of Autophagy in Ehrlichia-Induced Liver Injury', Cells, 12.
9. Aditya Kumar Sharma, Divya Arora, Lalit K Singh, Aakriti Gangwal, Andaleeb Sajid, Virginie Molle, Yogendra Singh, and Vinay Kumar Nandicoori. 2016. 'Serine/threonine protein phosphatase PstP of Mycobacterium tuberculosis is necessary for accurate cell division and survival of pathogen', Journal of Biological Chemistry, 291: 24215-30.
10. Aditya Kumar Sharma*, Neha Dhasmana*, and Gunjan Arora*. 2023. "Bridging the Gap: Exploring the Connection between Animal and Human Health." In, 176-78. MDPI.
11. Aditya Kumar Sharma*, and Anil K Giri*. 2024. 'Engineering CRISPR/Cas9 therapeutics for cancer precision medicine', Frontiers in Genetics, 15.
12. Aditya Kumar Sharma, and Nahed Ismail. 2023b. 'Non-Canonical Inflammasome Pathway: The Role of Cell Death and Inflammation in Ehrlichiosis', Cells, 12: 2597.
13. Lalit K Singh, Neha Dhasmana, Shashank S Kamble, Aditya Kumar Sharma, and Yogendra Singh. 2015. 'Frontiers in Biomedical Engineering: PHA-Fabricated Implants.' in, Microbial Factories: Biodiversity, Biopolymers, Bioactive Molecules: Volume 2 (Springer).
14. Biplab Singha, Sumit Murmu, Tripti Nair, Rahul Singh Rawat, Aditya Kumar Sharma*, and Vijay Soni*. 2024. 'Metabolic Rewiring of Mycobacterium tuberculosis upon Drug Treatment and Antibiotics Resistance', Metabolites, 14: 63.
15. Astrid Skjesol, Mariia Yurchenko, Korbinian Bösl, Caroline Gravastrand, Kaja Elisabeth Nilsen, Lene Melsæther Grøvdal, Federica Agliano, Francesco Patane, Germana Lentini, Hera Kim, Giuseppe Teti, Aditya Kumar Sharma, Richard K Kandasamy, Bjørnar Sporsheim, Kristian K Starheim, Douglas T Golenbock, Harald Stenmark, Mary McCaffrey, Terje Espevik, Harald Husebye 2019. 'The TLR4 adaptor TRAM controls the phagocytosis of Gram-negative bacteria by interacting with the Rab11-family interacting protein 2', PLoS pathogens, 15: e1007684.
16. Omid Teymournejad, Aditya Kumar Sharma, Mohammed Abdelwahed, Muhamuda Kader, Ibrahim Ahmed, Hoda Elkafas, and Nahed Ismail. 2023. 'Hepatocyte-specific regulation of autophagy and inflammasome activation via MyD88 during lethal Ehrlichia infection'.