Chemistry

Dr. Romila Manchanda
Father's Name:
Designation: Professor
Date of Birth:
Degree(s): Postdoc (Florida International University, Miami, USA); Ph.D. (IGIB (CSIR), CCS University, India); M. Sc. (Delhi University, India); BSc.(Delhi University, India)
Dr. Romila Manchanda

Research Area

 

Nanotechnology, Cancer, trigger release.

 

Professional Experience

 

Research Experience: 7 year, Teaching Experience:1. 5 years.

 

Subjects Taught

 

Chemistry, Environment Studies, biological chemistry etc.

 

Publications

 

  • Simultaneous Delivery of Chemotherapeutic and Thermal-Optical Agents to Cancer Cells by a Polymeric (PLGA) Nanocarrier: an In Vitro Study. Yuan Tang, Tinjguin Lei, Romila Manchanda, Abhignyan Nagesetti, Alicia Fernandez- Fernandez, Supriya Srinivasan, Anthony J. McGoron. (2010) Pharmaceutical Research, 27, 2242-2253.
  • Preparation and characterization of a polymeric (PLGA) nanoparticulate drug delivery system with simultaneous incorporation of chemotherapeutic and thermo-optical”: Romila Manchanda, Alicia. Fernanderz-Fernanderz, Abhignyan Nagesetti, Anthony J.McGoron. (2010), Colloids and Surfaces B: Biointerfaces, 75, 260-267.
  • Artificial oxygen carrier based on polysaccharides- poly(alkylcyanoacrylates) nanoparticle templates”: Cédric Chauvierre, Romila Manchanda, Denis Labarre, Christine Vauthier, Michael C. Marden, Liliane Leclerc, Biomaterials . (2010) 31, 6069-6074.
  • Controlled Size Chitosan Nanoparticles as an efficient, Biocompatible Oligonucleotides delivery System”: Romila Manchanda, Surendra Nimesh,  Journal of Applied polymer science. (2010) 118(4):2071-2077.
  • Comparing Cellular Uptake and Cytotoxicity of Targeted Drug Carriers in Cancer Cell Lines with Different Drug Resistance Mechanisms”: Tinjguin Lei, Supriya Srinivasan, Yuan Tang, Romila Manchanda, Abhignyan Nagesetti, Alicia Fernandez-Fernandez, Anthony J., Nanomedicine: Nanotechnology, Biology and Medicine (2011) 7(3) 324-332.
  • A Comparative Study of Optical and Heat Generation Properties of IR820 and Indocyanine Green”: Alicia Fernandez-Fernandez, Romila Manchanda, Tingjun Lei, Denny A.  Carvajal, Yuan Tang, Syed Zahid Raza Kazmi, Anthony J. McGoron, Molecular Imaging., (2012) Apr 1;11(2):99-113. PubMed ID: 22469238.
  • Nanoplexes for Cell Imaging and Hyperthermia: In vitro Studies”: Romila Manchanda, Alicia Fernandez-Fernandez, Denny A Carvajal, Tingjun Lei, Yuan Tang, Anthony J McGoron, J Biomed Nanotechnol. (2012) 8(4):686-694. PubMed ID: 22852478.
  • Near-infrared fluorescing IR820-chitosan conjugate for           multifunctional cancer theranostic applications”:, Supriya Srinivasan, Romila Manchanda, Alicia Fernandez-Fernandez, Tinjguin  Lei, Anthony J. McGoron,   J Photochem Photobiol B. (2013).

Book Chapter and Review

  • Drug Delivery through Multifunctional Polymeric Nanoparticles. (Invited). Romila Manchanda* and AnthonyJ.McGoron. Book chapter accepted for publication (Nova Science Publishers Inc., US) 2011.
  • Theranostic applications of nanomaterials in cancer: Image-guided therapy and multifunctional platforms. (2011). Alicia Fernandez-Fernandez, Romila Manchanda, Anthony J McGoron. (Invited review). Applied Biochemistry and Biotechnology.165(7-8):1628-51. PubMed ID: 21947761 

Conference Papers

 

  • Romila Manchanda, Abhignyan Nagesetti, Alicia Fernandez-Fernandez, Anthony J. McGoron. (2009). Development of a PLGA nanoparticlesth drug delivery system containing imaging/Hyperthermia/Chemotherapy agents. 25th  Southern Biomedical Engineering Conference.
  • Romila Manchanda, Tinjguin Lei, Yuan Tang, Alicia Fernandez-Fernandez, Anthony J. McGoron.(2010) Cellular Uptake and Cytotoxicity of a Novel ICG-DOX-PLGA Dual Agent Polymer Nanoparticle Delivery System. IFMBE Proceedings 32, p. 228-231.
  • Romila Manchanda, Yin.C. Huang, Tinjguin Lei, Alicia Fernandez-Fernandez, Anthony J. McGoron. (2010).Novel biodegradable PGD Polymeric Nanoparticles: Preparation and Characterization. Biomedical Engineering Society Annual Meeting, Austin, TX. Oct 6-9.
  • Tinjguin Lei, Supriya Srinivasan, Yuan Tang, Romila Manchanda, Alicia Fernandez-Fernandez, Anthony J. Mcgoron. (2010).Targeted Delivery of Doxorubicin by PLGA Nanoparticles Increases Drug Uptake in Cancer Cell Lines. IFMBE
  • Proceedings 32, p. 224-227.
  • Tingjun Lei, Alicia Fernandez-Fernandez, Yuan Tang, Denny Carvajal, Romila Manchanda, Syed Zahid Raza Kazmi, Anthony J. McGoron. (2010). Comparative study of IR-820 and Indocyanine green (ICG). Society of Nuclear Medicine. (June 9).
  • Alicia Fernandez-Fernandez, Romila Manchanda, Tinjguin Lei, Yuan Tang, Deny Carvajal, Anthony J. McGoron. (2011). IR820-PEG-diamine nanocomplexes for image- guided hyperthermia. Nanoflorida September30-October1.Miami.FL.
  • Supriya Srinivasan, Romila Manchanda, Alicia Fernendez-Fernendez, Tinjguin Lei, Anthony J McGoron,(2011). Near Infrared IR820-chitosan conjugate: Invitrostudies Biomedical Engeenering Society Annual meeting, October 12-15, Hartford, CT.
  • Romila Manchanda, Tinjguin lei, Yin C Huang, Anthony J McGoron Near infrared imaging(NIR) loaded polymeric nanoparticles: invitro studies. Nanoflorida 2011: The 4th annual nanoscience Technology symposium, Miami FL.
  • Alicia Fernandez-Fernandez, Romila Manchanda, Tinjguin Lei, Supriya Srinivasan, Anthony J. McGoron. (2012) Covalent IR820-PEG diamine nanoconjugate for imaging and hyperthermia. NanoFlorida. Tampa.
  • Alicia Fernandez-Fernandez, Romila Manchanda , Tinjguin Lei , Supriya Srinivasan ,Deny Carvajal , Anthony J McGoron, (2012). IR820 conjugates: theranostic applications in cancer. NBCIC
  • Alicia Fernandez-Fernandez ,Romila Manchanda , Tinjguin Lei, Supriya Srinivasan S, Anthony J. McGoron , (2012). IR820 conjugates for image-guided cancer therapy. World Congress of Medical Physics and Biomedical Engineering.
  • Tinjguin Lei, Romila Manchanda, Anthony J McGoron. (2012) In vitro and In vivo studies of near-infrared imaging (NIR) loaded polymeric nanoparticles. Nanoflorida . Tampa.
  • Tinjguin Lei, Romila Manchanda, Y-C Huang, Anthony J. McGoron, Simultaneous delivery of chemotherapeutic and hyperthermia agents using polymeric nanoparticles: an in vitro study., World Congress 2012 Medical Physics and Biomedical Engineering, May 26-31, 2012, Beijing, China.
  • Tinjguin Lei, Supriya Srinivasan, Yuan Tang, Romila Manchanda , Abhignyan Nagesetti, Alicia Fernandez-Fernandez, Anthony J. McGoron , Simultaneous delivery of chemotherapeutic and thermal-optical agents to cancer cells by a polymeric nanocarrier: an in vitro study. BIT's 5th Annual World Congress of Cancer, May 18-20, 2012, Beijing, China
  • Fernandez-Fernandez, A., R. Manchanda, D.A. Carvajal, T. Lei, and A.J. McGoron. Covalent IR820-PEG diamine conjugates: Characterization and in vivo biodistribution. Proceedings of SPIE BiOS 2013.
  • Tingjun Lei, Romila Manchanda, Yen-Chih Huang, Alicia Fernandez-Fernandez,Karina Bunetska, Andrew Milera, Azael Sarmiento,Anthony J. McGoron Near-infrared imaging loaded polymeric nanoparticles: In vitro and In vivo studies .2013 Proceedings of SPIE 2013. In press. 2 February 2013 to 7 February 2013 in San Francisco, California USA.
  • Tingjun Lei, Anthony McGoron, Romila Manchanda, Alicia Fernandez-Fernandez, Yen-Chih Huang. Theranostic nanoparticles for imaging and therapy and cellular response after laser-induced heating. Accepted for oral presentation. SBEC2013. 2- 5 may,2013 in Miami, USA
  • Alicia Fernandez-Fernandez, RomilaManchanda, Denny A. Carvajal, Tingjun Lei, Anthony J McGoron. Multifunctional Covalent Nanoconjugate for Near-Infrared Imaging and Hyperthermia.Accepted for oral presentation. SBEC 2013. 2-5 May 2013 in Miami, USA.
  • Anthony J. McGoron, Supriya Srinivasan, Tingjun Lei, Yuan Tang, and Romila Manchanda . Combined photothermal therapy and chemotherapy in cancer using HER-2 targeted PLGA nanoparticles, SPIE, 2013.

Posters

  • Alicia Fernandez-Fernandez , Romila Manchanda , Tinjguin Lei, Deny Carvajal , Anthony J. McGoron. Novel IR820-PEG-diamine nanoparticles for combined imaging and therapy: in vitro studies. BMES 2010. Poster presentation
  • Targeted delivery of indocyanine green and doxorubicin simultaneously loaded
  • poly(lactide-co-glycolide) (PLGA) nanoparticles: An in vitro study. An AACR Special Conference on Nano in Cancer. January 12-15, 2011, Miami, FL.
  • A Novel dual agent loaded PLGA nanoparticles for simultaneous delivery of  chemotherapy and Hyperthermia. Biomedical Engineenering Society. (2010).
  • Near-Infrared IR820-Chitosan Conjugate: In Vitro Studies.Biomedical Engineering Society.( 2011)
  • Fernandez-Fernandez A, R. Manchanda, T. Lei, and A.J. McGoron. Preparation and Characterization of Covalent IR820-PEG Diamine Conjugates. BMES 2012 October24- 27 Atlanta GA.
  • Tinjguin Lei, Romila Manchanda , YC Huang, Anthony J McGoron. Thermal and pH Sensitive Multifunctional Polymer nanoparticles for Cancer Therapy. BMES 2012 Atlanta
  • Supriya Srinivasan, Romila Manchanda , Alicia Fernandez-Fernandez , Tinjguin Lei , Anthony J McGoron. Near-infrared IR820-chitosan conjugates: in vitro studies BMES 2011.
  • Alicia Fernandez-Fernandez, Romila Manchanda, Supriya Srinivasan, Tinjguin Lei, Dany Carvajal, Anthony J. McGoron. IR820-chitosan conjugates for imaging and hyperthermia. SNM 2012 [J Nucl Med. 2012; 53 (Suppl. 1):1172].
  • Tinjguin Lei, Alicia Fernandez-Fernandez, Yuan Tang, Dany Carvajal, Romila Manchanda, Sayed Z Kazmi, Anthony J. McGoron. A comparative study of IR-820 and indocyanine green (ICG). J Nucl Med. 2010; 51 (S2):225.
  • Co-delivery of near-infrared (NIR) imaging and chemotherapeutic agent  using polymeric nanoparticles.(2012) SNM 2012 Annual Meeting at the Miami Beach Convention Center, Miami, Florida, June 9-13, 2012
  • Romila Manchanda, Alenjedro Amor, Seza Gulec, Anthony J McGoron, Chitosan Microspheres: Therapeutic Agent for Liver-directed Radiomicrosphere Therapy. (2012) SNM Annual Meeting, held June 9-13, Miami Beach Convention Center

Awards & Honors

  • Young Inventor Award, FIU Foundation. 
 
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